Bertold Hock: Bioresponse-Linked Instrumental Analysis, Kartoniert / Broschiert

Kurzbeschreibung

Aktuelle Forschungsergebnisse

Beschreibung

Die wirkungsbezogene Analytik befasst sich mit der engen Kopplung von Biotests mit der chemischen Analytik. Hierbei werden die biomolekulare Erkennung, die im Organismus einen biologischen Effekt auslöst, und die chemische Analytik kombiniert. Dieses Buch behandelt Fortschritte in der analytischen Instrumentation von biologischen Makromolekülen, welche die gekoppelten Technologien ermöglicht haben, insbesondere die automatische Kopplung von Bindungstests mit der chemischen Analytik. Bioresponse-linked instrumental analysis combines biomolecular recognition, initiating a biological effect in the organism, and chemical analysis. Although this technology is only at its beginning, the power of this approach is obvious. It provides both, information on effects with respect to the applied target structures as well as the chemical structure and concentration of active substances present in a sample. In this book, examples ranging from endocrine disruptors to neurotoxic substances are used to illustrate the principle.

Inhaltsangabe

Aus dem Inhalt:
- Approaches to Bioresponse-Linked Instrumental Analysis
- Detection of Bioeffective Environmental Componds by High-Performance Thin Layer Chromatography
- Electronic Noses
- Receptors as Analytical Tools for Bioresponse
- Bioresponse-Linked Analysis Based on Acetylcholinesterase Inhibition
- Transport Proteins in Blood
- Biomonitor Systems Derived from Thylakoids for the Detection of Phytotoxic Substances

Klappentext

Bioresponse-linked instrumental analysis combines biomolecular recognition, initiating a biological effect in the organism, and chemical analysis. Although this technology is only at its beginning, the power of this approach is obvious. It provides both, information on effects with respect to the applied target structures as well as the chemical structure and concentration of active substances present in a sample. In this book, examples ranging from endocrine disruptors to neurotoxic substances are used to illustrate the principle.